Drugs that Do Not Combine Well with Medical Marijuana

In general, cannabis or medical marijuana is unlikely to interact negatively with most prescription drugs. When taking prescriptions, however, it is vital to meet with a medical practitioner and report cannabis use. Physicians and pharmacists are not allowed to inquire about the medical card. They won't be able to give you lifesaving details about drug reactions unless you tell them.

There hasn't been a single instance of a fatal overdose caused solely by marijuana. When you ingest too much cannabis, you can experience toxic symptoms. Those symptoms, on the other hand, usually go away without medical help. And they can be so nasty that even the most casual cannabis user knows when they've reached their limit.

There aren't many prescription medications that interact with medical marijuana. Many patients, however, use the following 7 drugs to treat ailments such as respiratory disease, epilepsy, and more. These drugs are also considered to have harmful interactions with cannabis.

Warfarin

When patients have a higher-than-normal chance of blood clots, warfarin is administered. Deep vein thrombosis is a condition in which blood clots form in the knee, thigh, or pelvis.

THC and CBD also inhibit the metabolic activity of CYP2C9, an enzyme that can cause warfarin levels to rise. This ensures an increased risk of bleeding as the INR ratio rises to dangerous levels, putting the patient at risk of life-threatening bleeding.

Valproate

Valproate is a medication used to treat epileptic seizures. This medication is also given to certain patients to help them control their bipolar disorder or migraine symptoms. Patients who took prescription Epidiolex (a CBD component) along with Valproate get three times more drug effect, according to some clinical reports. This raises the chances of liver damage.

Theophylline

Patients with serious respiratory problems such as asthma, bronchitis or emphysema are often administered theophylline. Marijuana that can be smoked causes the medication to dissipate or metabolize rapidly, making it less effective. Other cannabis products, such as tincture drops oredibles, do not have the same harmful effects.

Clobazam

Clobazami.e. benzodiazepine is used to control seizures in both children and adults with Lennox-Gastaut syndrome. CBD inhibits CYP2C219, which is why the FDA permitted the first cannabis-derived epilepsy drug (Epidolex). Clobazam's efficacy is reduced, and the drug's concentration in blood plasma will rise. This can lead to a higher degree of sedation or sleepiness.

Suboxone and Subutex

Suboxone, Subutex, and Buprenorphine (as well as Buprenorphine) can be prescribed for patients suffering from opioid addiction to medications like heroin, Oxycodone, or Fentanyl. As part of a step-down drug treatment strategy, the drugs make the withdrawal symptoms manageable.

When using cannabis along with Subutex, Suboxone, or other Buprenorphine-containing medications, there are certain serious safety concerns. When cannabis is combined with this class of drugs, extreme depressive symptoms may occur. This can cause respiratory depression (breathing problems), which can be fatal.

Prescriptions for antidepressants and anti-anxiety medications

Benzodiazepines are a form of medication that is widely prescribed for anxiety, insomnia, and depression. Benzodiazepines, on the other hand, are known to cause memory disturbances. When cannabis and alcohol are consumed together, it can intensify memory loss by causing a ‘mental fog' and short-term memory loss.

Seroquel

Seroquel is a medication that is used to relieve the effects of bipolar disorder. Confusion, concentration issues, drowsiness, and dizziness are also possible side effects of the medication (Quetiapine). When Seroquel is combined with cannabis, it can affect movement and coordination.

See us at Frontier Medicine for medical marijuana. Take suggestions from our experts and follow the guideline of consuming. Our dispensary in OKC is open for 24 hours.

**Disclaimer: This content is not the advice of a doctor; no product promoted herein is approved by the FDA to treat, cure, or prevent any disease.